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Single‐cell transcriptomics uncovers cellular architecture and developmental trajectories in hepatoblastoma

5 Sept 2022

Abstract excerpt

BACKGROUND AND AIMS: Hepatoblastoma (HB) is the predominant type of childhood liver cancer. Treatment options for the clinically advanced HB remain limited. We aimed to dissect the cellular and molecular basis underlying HB oncogenesis and heterogeneity at the single-cell level, which could facilitate a better understanding of HB at both the biological and clinical levels. APPROACH AND RESULTS: Single-cell...

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PMID: 36059151
DOI: 10.1002/hep.32775

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