Article

Micropatterned substrates to promote and dissect reprogramming of human somatic cells

2017-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Reprogramming of human somatic cells to induce pluripotent stem cells (iPSCs) generates valuable precursors for disease modeling and regenerative medicine. However, the reprogramming process can be inefficient and noisy, creating many partially reprogrammed cells in addition to fully reprogrammed iPSCs. To address these shortcomings, we developed a micropatterned substrate that allows for dynami...

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Literature Corpus work: 9964c32d-6ebf-5627-99ae-83388116cfb5
DOI: 10.1101/111369

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