Article

Effects of C3aR activated mast cells in eosinophilic esophagitis

2025-05-28

Abstract excerpt

<h4>Background</h4> Eosinophilic esophagitis is a chronic food induced allergic inflammatory disease of the esophagus. Eosinophil-depleting antibodies have not shown significant improvement in clinical symptoms, which has turned attention to mast cells. These cells also accumulate in the esophagus of EoE at levels that correlate with symptoms, demonstrate extensive activation including degranulation, correlate an...

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Literature Corpus work: 9946394b-6856-565c-aad3-1dab61684cf3
DOI: 10.1101/2025.05.23.655738

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