Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overlapping type 2, barrier, and remodeling endotypes shape clinical expression in eosinophilic esophagitis.

Frontiers in immunology - 1 Jan 2026

Wawrzeńczyk Adam, Napiórkowska-Baran Katarzyna, Tykwińska Marta, Szota Maciej, Bartuzi Zbigniew, Sławatycki Józef, Kanikowska Alina, Pałgan Krzysztof

Abstract excerpt

Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease of the esophagus in which symptoms, histologic activity, endoscopic severity, epithelial dysfunction, and fibrostenotic remodeling frequently diverge. Peak eosinophil density remains central to diagnosis and response assessment, but it represents only one component of a broader epithelial-immune and structural process. This review integrates...

Read the complete abstract on PubMed

Topics

Humans
Eosinophilic Esophagitis
Eosinophils
Mast Cells
Animals
Interleukin-13

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Esophagus

Source

Open in PubMed Open full text

Identifiers

PMID: 42769530
DOI: 10.3389/fimmu.2026.1948419
PMCID: PMC13591616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overlapping type 2, barrier, and remodeling endotypes shape clinical expression in eosinophilic esophagitis.PMID 42769530Read ↗

Clinical heterogeneity and endotype stratification in eosinophilic esophagitis.Semantic proximity Read ↗

Esophageal epithelial cell-state transitions underlie the severity of pediatric eosinophilic esophagitisSemantic proximity Read ↗

Eosinophilic esophagitis phenotypes: Ready for prime time?Semantic proximity Read ↗

Eosinophilic Esophagitis beyond Eosinophils – an Emerging Phenomenon Overlapping with Eosinophilic Esophagitis: Collegium Internationale Allergologicum (CIA) Update 2023Semantic proximity Read ↗

Unmet therapeutic needs in eosinophilic esophagitis.Semantic proximity Read ↗

Phenotypes and endotypes in eosinophilic esophagitis.Semantic proximity Read ↗

Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study.Semantic proximity Read ↗

A phenotypic analysis shows that eosinophilic esophagitis is a progressive fibrostenotic disease.Semantic proximity Read ↗

Differential roles for IL-4Rα and IL-13Rα1 in immune cell infiltration and epithelial remodeling in experimental eosinophilic gastritisSemantic proximity Read ↗

IL-13 Induces Esophageal Remodeling and Gene Expression by an Eosinophil-Independent, IL-13Rα2–Inhibited PathwaySemantic proximity Read ↗

Biology and treatment of eosinophilic esophagitis.Semantic proximity Read ↗

Pediatric Eosinophilic Esophagitis Endotypes: Are We Closer to Predicting Treatment Response?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.