Article
Dietary treatment modulates mast cell phenotype, density, and activity in adult eosinophilic oesophagitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2016
Arias Á, Lucendo A J, Martínez-Fernández P, González-Castro A M, Fortea M, González-Cervera J, Yagüe-Compadre J L, Mota-Huertas T, Vicario M
Abstract excerpt
BACKGROUND: Mast cells (MCs) are abundant in the inflammatory infiltrate in eosinophilic oesophagitis (EoE), but decrease with disease remission. However, their phenotype, role in the pathophysiology of the disease, and modulation after effective dietary therapy are still unclear. OBJECTIVE: To define the phenotype of oesophageal MCs, their modulation through dietary therapy, and their association with clinical...
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