Article

Distinct roles for thymic stromal lymphopoietin (TSLP) and IL-33 in experimental eosinophilic esophagitis

2025-03-01

Abstract excerpt

<h4>Rationale</h4> Thymic stromal lymphopoietin (TSLP) and IL-33 are alarmins implicated in EoE pathogenesis by activating multiple cells including mast cells (MCs). Whether TSLP or IL-33 have a role in EoE and whether their activities are distinct requires further investigation. <h4>Methods</h4> Experimental EoE was induced in wild type (WT) Il33 -/- and Crlf2 -/- mice. TSLP or IL-5 were neutralized using a...

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Literature Corpus work: 0e7d6cce-22f6-53b8-92eb-5120a23c07be
DOI: 10.1101/2025.02.25.640192

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