Article

A comprehensive functional investigation of the human translocator protein 18 kDa (TSPO) in a novel human neuronal cell knockout model: from molecule to depression

2024-03-13

Abstract excerpt

<title>Abstract</title> <p>The translocator protein 18 kDa (TSPO) is a multifunctional outer mitochondrial membrane protein associated with various aspects of mitochondrial physiology and multiple roles in health and disease. Here, we aimed to analyze the impact of TSPO on the regulation of mitochondrial and cellular function in a human neuronal cell model. We used the CRISPR/Cas9 technology and generated TSPO kn...

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Literature Corpus work: 992a4281-eff8-588c-b433-c9ddfde816d8
DOI: 10.21203/rs.3.rs-4024118/v1

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