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The Role of Translocator Protein TSPO in Hallmarks of Glioblastoma

14 Oct 2020

Abstract excerpt

Glioblastoma (GBM) is the most fatal primary brain cancer in adults. Despite extensive treatment, tumors inevitably recur, leading to an average survival time shorter than 1.5 years. The 18 kDa translocator protein (TSPO) is abundantly expressed throughout the body including the central nervous system. The expression of TSPO increases in states of inflammation and brain injury due to microglia activation. Not...

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PMID: 33066460
DOI: 10.3390/cancers12102973

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