Article

A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics

2024-11-27

Abstract excerpt

<h4>ABSTRACT</h4> Manganese (Mn) is an essential trace metal that is necessary for life. Its duality as both a crucial micronutrient and potential neurotoxicant necessitates tight control of intracellular and extracellular Mn levels. Dysregulation of Mn is implicated in a broad range of human diseases, from neurodevelopmental sequelae related to Mn levels in drinking water, to acquired forms of manganism, rare in...

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Literature Corpus work: 7d9fac0c-8f7a-5d7c-9233-41455351bd06
DOI: 10.1101/2024.11.27.625600

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