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Article

History of Tspo deletion and induction in vivo: Phenotypic outcomes under physiological and pathological situations.

Biochimie - 1 Sept 2024

Bréhat Juliette, Issop Leeyah, Morin Didier

Abstract excerpt

The mitochondrial translocator protein (TSPO) is an outer mitochondrial protein membrane with high affinity for cholesterol. It is expressed in most tissues but is more particularly enriched in steroidogenic tissues. TSPO is involved in various biological mechanisms and TSPO regulation has been related to several diseases. However, despite a considerable number of published studies interested in TSPO over the...

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PMID: 38432291
DOI: 10.1016/j.biochi.2024.03.001

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