Article

Title: Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems

2021-05-05

Abstract excerpt

Glucose is an essential energy source for cells. In humans, its passive diffusion through the cell membrane is facilitated by members of the glucose transporter family (GLUT, SLC2 gene family). GLUT2 transports both glucose and fructose with low affinity and plays a critical role in glucose sensing mechanisms. Alterations in the function or expression of GLUT2 are involved in the Fanconi-Bickel syndrome, diabetes,...

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Literature Corpus work: 99002f92-26ff-5752-8b44-432e78006e2f
DOI: 10.21203/rs.3.rs-489875/v1

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