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Article

Crystal structure of the human glucose transporter GLUT1.

Nature - 5 Jun 2014

Deng Dong, Xu Chao, Sun Pengcheng, Wu Jianping, Yan Chuangye, Hu Mingxu, Yan Nieng

Abstract excerpt

The glucose transporter GLUT1 catalyses facilitative diffusion of glucose into erythrocytes and is responsible for glucose supply to the brain and other organs. Dysfunctional mutations may lead to GLUT1 deficiency syndrome, whereas overexpression of GLUT1 is a prognostic indicator for cancer. Despite decades of investigation, the structure of GLUT1 remains unknown. Here we report the crystal structure of human...

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Identifiers

PMID: 24847886
DOI: 10.1038/nature13306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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