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MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans

2022-04-10

Abstract excerpt

Transcription factors (TFs) show heterogeneous DNA-binding specificities in individual cells and whole organisms in natural conditions): de novo motif discovery usually provides multiple motifs even from a single ChIP-seq sample. Despite the accumulation of ChIP-seq data and ChIP-seq-derived motifs, the diversity of DNA-binding specificities across different TFs and cell types remains largely unexplored. Here, we...

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Literature Corpus work
98c74936-c03f-5e46-89ef-ce4fec0a9f20
DOI
10.1101/2022.04.08.487641
Open publication

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MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humansDOI 10.1101/2022.04.08.487641
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