Genome-wide association study of varicose veins identifies a protective missense variant in GJD3 enriched in the Finnish population

Abstract excerpt

Abstract Varicose veins is the most common manifestation of chronic venous disease that displays female-biased incidence. To identify protein-inactivating variants that could guide identification of drug target genes for varicose veins and genetic evidence for the disease prevalence difference between the sexes, we conducted a genome-wide association study of varicose veins in Finns using the FinnGen dataset with...

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