Article

RIG-I is an intracellular checkpoint that limits CD8+ T-cell antitumor immunity

2023-05-17

Abstract excerpt

<h4>Background: </h4> Although a variety of immune checkpoint monoclonal antibodies have been approved for the treatment of cancers, the low response rate of immune checkpoint inhibitors limits their wide clinical application. Therefore, to explore new and broader immunotherapy targets to improve the response rate of CD8 + T cells will provide theoretical basis for clinical treatment of refractory malignant solid...

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Literature Corpus work: 982e32d9-4976-551b-a2b3-d34d58c6d590
DOI: 10.21203/rs.3.rs-2931210/v1

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