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Article

The Innate Immune Signalling Pathways: Turning RIG-I Sensor Activation against Cancer

27 Oct 2020

Abstract excerpt

Over the last 15 years, the ability to harness a patient's own immune system has led to significant progress in cancer therapy. For instance, immunotherapeutic strategies, including checkpoint inhibitors or adoptive cell therapy using chimeric antigen receptor T-cell (CAR-T), are specifically aimed at enhancing adaptive anti-tumour immunity. Several research groups demonstrated that adaptive anti-tumour immunity...

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PMID: 33121210
DOI: 10.3390/cancers12113158

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