Article

Novel Myostatin-Specific Antibody Enhances Muscle Strength in Muscle Disease Models

2020-12-08

Abstract excerpt

Myostatin, a member of the transforming growth factor-b superfamily, is an attractive target for muscle disease therapy because of its role as a negative regulator of muscle growth and strength. Here, we describe a novel antibody therapeutic approach that maximizes the potential of myostatin-targeted therapy. We generated an antibody, GYM329, that specifically binds the latent form of myostatin and inhibits its ac...

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Identifiers and source

Literature Corpus work: 9812c415-3d69-5ae2-97a7-c875303dfa23
DOI: 10.21203/rs.3.rs-116413/v1

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