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Article

[Myostatin blockade therapy for muscular atrophy].

Brain and nerve = Shinkei kenkyu no shinpo - 1 Nov 2011

Sunada Yoshihide

Abstract excerpt

Myostatin, a member of the muscle-specific transforming growth factor (TGF)-β family, negatively regulates skeletal muscle growth. It inhibits muscle stem cell proliferation and differentiation and attenuates adult muscle fiber protein accretion, resulting in decreased skeletal muscle mass. As such, it has been considered a therapeutic target of muscular dystrophy. Notably, administration of a blocking antibody...

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Share to Activin Receptors, Type II
Share to Antibodies, Neutralizing
Share to Molecular Targeted Therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscular Atrophy

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Share to Protein Structure, Tertiary

Share to RNA, Small Interfering

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Identifiers

PMID: 22068480

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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