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Therapeutic applications and challenges in myostatin inhibition for enhanced skeletal muscle mass and functions

28 Sept 2024

Abstract excerpt

Myostatin, a potent negative regulator of skeletal muscle mass, has garnered significant attention as a therapeutic target for muscle dystrophies. Despite extensive research and promising preclinical results, clinical trials targeting myostatin inhibition in muscle dystrophies have failed to yield substantial improvements in muscle function or fitness in patients. This review details the mechanisms behind...

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Adipose Tissue and Metabolism
Muscle Physiology and Disorders

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39340593
DOI: 10.1007/s11010-024-05120-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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