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Article

Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19

2021-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal models that reflect genetic diversity and clinical outcomes observed in humans are needed. We report a mouse panel comprising the genetically diverse Collabora...

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Identifiers and source

Literature Corpus work
9800101a-d13d-5655-838f-0f3837a09ecf
DOI
10.1101/2021.09.17.460664
Open publication

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Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19DOI 10.1101/2021.09.17.460664
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