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Animal models for SARS-Cov2/Covid19 research-A commentary

1 Apr 2021

Abstract excerpt

INTRODUCTION: There is an urgent need for new animal models of SARS CoV-2 infection to improve research and drug development. This brief commentary examines the deficits of current models and proposes several improved alternates. The existing single transgene mouse models poorly mimic the clinical features of COVID-19; those strains get a milder disease than human COVID-19 disease. Many of the current transgenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33812856
DOI: 10.1016/j.bcp.2021.114543

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