Article

Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach

2019-01-03

Abstract excerpt

<h4>SUMMARY</h4> Alzheimer’s disease (AD) is a complex and heterogenous brain disease that affects multiple inter-related biological processes. This complexity contributes, in part, to existing difficulties in the identification of successful disease-modifying therapeutic strategies. To address this, systems approaches are being used to characterize AD-related disruption in molecular state. To evaluate the consis...

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Literature Corpus work: 61e6eafb-39e1-5776-984e-0010d815dd14
DOI: 10.1101/510420

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