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The transcription factor IscR promotes <i>Yersinia</i> type III secretion system activity by antagonizing the repressive H-NS-YmoA histone-like protein complex

2021-10-27

Abstract excerpt

The type III secretion system (T3SS) is a appendage used by many bacterial pathogens, such as pathogenic Yersinia , to subvert host defenses. However, because the T3SS is energetically costly and immunogenic, it must be tightly regulated in response to environmental cues to enable survival in the host. Here we show that expression of the Yersinia Ysc T3SS master regulator, LcrF, is orchestrated by the opposing a...

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Identifiers and source

Literature Corpus work
97cd52f6-ea22-51f9-a508-2e6b460e1c04
DOI
10.1101/2021.10.26.466021
Open publication

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The transcription factor IscR promotes <i>Yersinia</i> type III secretion system activity by antagonizing the repressive H-NS-YmoA histone-like protein complexDOI 10.1101/2021.10.26.466021
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