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Article

Sequence-specific binding to a subset of IscR-regulated promoters does not require IscR Fe-S cluster ligation.

Journal of molecular biology - 20 Mar 2009

Nesbit A D, Giel J L, Rose J C, Kiley P J

Abstract excerpt

IscR is an Fe-S protein that functions as a transcriptional regulator of Fe-S biogenesis and other Fe-S protein-encoding genes in Escherichia coli. In this study, we investigated the requirement for the ligation of the [2Fe-2S] cluster of IscR to regulate a subset of IscR target promoters (P(hyaA), P(ydiU), P(napF), and P(hybO)) and defined the requirements for sequence-specific binding to the IscR target site in...

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Identifiers

PMID: 19361432
DOI: 10.1016/j.jmb.2009.01.055
PMCID: PMC2709974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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