Article

<i>Yersinia</i> remodels epigenetic histone modifications in human macrophages

2021-09-07

Abstract excerpt

Various pathogens systematically reprogram gene expression in macrophages, but the underlying mechanisms are largely unknown. We investigated whether the enteropathogen Yersinia enterocolitica alters chromatin states to reprogram gene expression in primary human macrophages. Genome-wide chromatin immunoprecipitation (ChIP) seq analyses showed that pathogen-associated molecular patterns (PAMPs) induced up- or down...

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Literature Corpus work: 507e360b-2fd2-5e8e-83f9-9c07bef3c4ca
DOI: 10.1101/2021.09.07.459276

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