Article

Short-hairpin RNA-guided single gene knockdown reverses triple-negative breast cancer

2018-09-15

Abstract excerpt

<h4>Background</h4> The origin of breast cancer remains poorly understood. Here, we testify a putative mechanism of “breast cancer origin from inducible nitric oxide synthase (iNOS) activation and oestrogen receptor alpha (ERα) inactivation”, which are classified as the essential outcomes of chronic inflammatory responses. <h4>Methods</h4> To reverse breast cancer status, iNOS was downregulated by short-hairpin...

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Literature Corpus work: 97c16458-2e4e-5ea3-bb00-bd4e40abcf3e
DOI: 10.1101/418764

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