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Article

The Role of Nitric Oxide in Cancer: Master Regulator or NOt?

10 Dec 2020

Abstract excerpt

Nitric oxide (NO) is a key player in both the development and suppression of tumourigenesis depending on the source and concentration of NO. In this review, we discuss the mechanisms by which NO induces DNA damage, influences the DNA damage repair response, and subsequently modulates cell cycle arrest. In some circumstances, NO induces cell cycle arrest and apoptosis protecting against tumourigenesis. NO in other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33321789
DOI: 10.3390/ijms21249393

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