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Article

Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer.

Breast cancer research : BCR - 12 Sept 2012

Switzer Christopher H, Cheng Robert Y-S, Ridnour Lisa A, Glynn Sharon A, Ambs Stefan, Wink David A

Abstract excerpt

INTRODUCTION: The Ets-1 transcription factor is a candidate breast cancer oncogene that regulates the expression of genes involved in tumor progression and metastasis. Ets-1 signaling has also been linked to the development of a basal-like breast cancer phenotype. We recently described a nitric oxide (NO)-induced gene signature that is associated with poor disease outcome in estrogen receptor-negative (ER-)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Nitric Oxide Synthase Type II

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Source

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Identifiers

PMID: 22971289
DOI: 10.1186/bcr3319
PMCID: PMC4053102

Genes

NOS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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