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Conserved transcriptional programming across sex and species after peripheral nerve injury predicts treatments for neuropathic pain

19 Jun 2023

Abstract excerpt

BACKGROUND AND PURPOSE: Chronic pain is a devastating problem affecting one in five individuals around the globe, with neuropathic pain the most debilitating and poorly treated type of chronic pain. Advances in transcriptomics have contributed to cataloguing diverse cellular pathways and transcriptomic alterations in response to peripheral nerve injury but have focused on phenomenology and classifying...

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PMID: 37336547
DOI: 10.1111/bph.16168

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