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scRNA-sequencing reveals subtype-specific transcriptomic perturbations in DRG neurons of <i>Pirt-EGFPf</i> mice in neuropathic pain condition

2022-01-06

Abstract excerpt

Functionally distinct subtypes/clusters of dorsal root ganglion (DRG) neurons, which differ in soma size and neurochemical properties, may play different roles in nerve regeneration and pain. However, details about transcriptomic changes in different neuronal subtypes under maladaptive neuropathic pain conditions remain unclear. Chronic constriction injury (CCI) of the sciatic nerve represents a well-established m...

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Literature Corpus work
4e66ea42-56f4-5f23-b80b-0b30fb3a42c0
DOI
10.1101/2022.01.06.475187
Open publication

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scRNA-sequencing reveals subtype-specific transcriptomic perturbations in DRG neurons of <i>Pirt-EGFPf</i> mice in neuropathic pain conditionDOI 10.1101/2022.01.06.475187
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