Article

Spinal signatures of entrenched and treated neuropathic pain

2024-10-11

Abstract excerpt

<title>Abstract</title> <p>Chronic pain arises from an imbalance between excitation and inhibition. For chronic pain caused by peripheral nerve injury, sensory neuron damage leads to changes in spinal pain transduction, where enhanced excitatory and/or loss of inhibitory pathways can drive pain diseases. At the cellular level, the transcriptional changes occurring in entrenched chronic pain are largely unknown. H...

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Literature Corpus work: 7ee90327-0677-56d1-a152-245b1cca4949
DOI: 10.21203/rs.3.rs-4796294/v1

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