Article
Iron chelation as a new therapeutic approach to prevent senescence and liver fibrosis progression
2024-06-07
Abstract excerpt
<title>Abstract</title> <p>Iron overload and cellular senescence have been implicated in liver fibrosis, but their possible mechanistic connection has not been explored. To address this, we have deepened into the role of iron and senescence in an experimental model of chronic liver injury, analyzing whether an iron chelator would prevent liver fibrosis by decreasing hepatocyte senescence. The model of carbon tetr...
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Identifiers and source
- Literature Corpus work
- 975e419f-2698-59a7-972a-bda2b4d2dd0c
- DOI
- 10.21203/rs.3.rs-4376183/v1