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Aging and Aging-Related Senescence in Liver

4 Jul 2025

Abstract excerpt

Aging is characterized by the progressive deterioration of cell and tissue functions. The liver, which regulates metabolic homeostasis, detoxification, and immune responses, undergoes structural and functional changes with age. These include increasing genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing and intracellular communication, mitochondrial...

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PMID: 40614770
DOI: 10.1055/a-2637-2549

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