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Article

Iron accumulation during cellular senescence.

Annals of the New York Academy of Sciences - 1 Jun 2004

Killilea David W, Wong Stephanie L, Cahaya Hendry S, Atamna Hani, Ames Bruce N

Abstract excerpt

Iron accumulates as a function of age and is associated with the pathology of numerous age-related diseases. These changes may be caused by altered iron homeostasis at the cellular level, yet this is poorly understood. Therefore, changes in iron content in primary human fibroblasts were studied in culture models of cellular senescence. Total iron content increased exponentially during cellular senescence,...

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PMID: 15247045
DOI: 10.1196/annals.1297.063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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