Article
Delineating the heterogeneity of senescence-induced-functional alterations in hepatocytes
2023-09-05
Abstract excerpt
<h4>Background and Aim</h4> Cellular senescence of hepatocytes involves permanent cell cycle arrest, disrupted cellular bioenergetics, resistance to cell death, and the release of pro-inflammatory cytokines. This ’zombie-like’ state perpetuates harmful effects on tissues and holds potential implications for liver disease progression. Remarkably, senescence exhibits heterogeneity, stemming from two crucial factors...
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Identifiers and source
- Literature Corpus work
- a2dcd934-3472-5f38-b34f-f00eaf3c8491
- DOI
- 10.1101/2023.09.04.556220