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Iron Metabolism in Cancer and Senescence: A Cellular Perspective

11 Jul 2023

Abstract excerpt

Iron participates in a number of biological processes and plays a crucial role in cellular homeostasis. Alterations in iron metabolism are considered hallmarks of cancer and drivers of aggressive behaviors, such as uncontrolled proliferation, resistance to apoptosis, enhanced metastatic ability, increased cell plasticity and stemness. Furthermore, a dysregulated iron metabolism has been associated with the...

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PMID: 37508419
DOI: 10.3390/biology12070989

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