Article

Modelling eNvironment for Isoforms (MoNvIso): A general platform to predict structural determinants of protein isoforms in genetic diseases

2022-04-22

Abstract excerpt

The seamless integration of human disease-related mutation data into protein structures is an essential component of any attempt to correctly assess the impact of the mutation. The key step preliminary to any structural modelling is the identification of the correct isoform onto which mutations should be mapped because there are several functionally different protein isoforms from the same gene. To handle large se...

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Literature Corpus work: a203fc0c-aff3-5e51-b7a1-b46dc5a70eeb
DOI: 10.1101/2022.04.21.489045

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