Article

Patrolling human SLE haematopoietic progenitors demonstrate enhanced extramedullary colonisation; implications for peripheral tissue injury

2021-01-15

Abstract excerpt

<h4>ABSTRACT</h4> Systemic Lupus erythematosus (SLE) is an autoimmune disease where bone-marrow-derived haematopoietic cells have a key role in its pathogenesis with accumulating evidence suggesting an aberrant function of haematopoietic stem/progenitor cells (HSPCs). By employing next-generation sequencing, we compared the gene transcription signatures of CD34 + HSPCs deriving from either the bone marrow or HSP...

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Literature Corpus work: 96f5d168-f631-586e-8ba9-f0161e2840ba
DOI: 10.1101/2021.01.15.426761

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