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Interleukin-1α and Leukemia Inhibitory Factor Promote Extramedullary Hematopoiesis

2022-07-08

Abstract excerpt

Extramedullary hematopoiesis (EMH) expands hematopoietic capacity outside of the bone marrow in response to inflammatory conditions, including infections and cancer. Because of its inducible nature, EMH offers a unique opportunity to study the interaction between hematopoietic stem and progenitor cells (HSPCs) and their niche. In cancer patients, the spleen frequently serves as an EMH organ and provides myeloid ce...

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Identifiers and source

Literature Corpus work
21523e0f-e9c3-5d8c-a6d2-c60bda0dfcf1
DOI
10.1101/2022.07.07.499256
Open publication

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