Article

Paracrine factors of stressed peripheral blood mononuclear cells activate pro-angiogenic and anti-proteolytic processes in whole blood cells and protect the endothelial barrier

2022-04-22

Abstract excerpt

Tissue regenerative properties have been attributed to secreted paracrine factors derived from stem cells and other cell types. Especially, the secretome of γ-irradiated peripheral blood mononuclear cells (PBMCsec) has been shown to possess high tissue-regenerative and pro-angiogenic capacities in a variety of preclinical studies. In the light of future therapeutic intravenous applications of PBMCsec, we investiga...

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Literature Corpus work: 4965672e-722e-54fd-9dee-1b0d436f11cd
DOI: 10.1101/2022.04.22.489132

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Paracrine factors of stressed peripheral blood mononuclear cells activate pro-angiogenic and anti-proteolytic processes in whole blood cells and protect the endothelial barrierDOI 10.1101/2022.04.22.489132Read

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