Article

Coupling of translation quality control and mRNA targeting to stress granules

2020-01-06

Abstract excerpt

Stress granules (SGs) are dynamic assemblies of non-translating RNAs and proteins that form with translation inhibition 1 . Stress granules are similar to neuronal and germ cell granules, play a role in survival during stress, and aberrant, cytotoxic SGs are implicated in neurodegeneration 2–4 . Perturbations in the ubiquitin-proteasome (UPS) system also cause neurodegeneration 5–10 , and alter the dynamicity a...

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Literature Corpus work: 96b469c9-ec72-5a30-8178-cc8a9b909c44
DOI: 10.1101/2020.01.05.895342

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