Article
Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function.
Cell - 20 Jun 2013
Buchan J Ross, Kolaitis Regina-Maria, Taylor J Paul, Parker Roy
Abstract excerpt
Stress granules and P bodies are conserved cytoplasmic aggregates of nontranslating messenger ribonucleoprotein complexes (mRNPs) implicated in the regulation of mRNA translation and decay and are related to RNP granules in embryos, neurons, and pathological inclusions in some degenerative diseases. Using baker's yeast, 125 genes were identified in a genetic screen that affected the dynamics of P bodies and/or...
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