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An Indicator Cell Assay-based Multivariate Blood Test for Early Detection of Alzheimer’s Disease

2025-09-15

Abstract excerpt

The indicator cell assay platform (iCAP) is a novel next-generation approach for blood-based diagnostics that uses standardized cells as biosensors to amplify weak disease signals in blood. We developed an Alzheimer’s disease iCAP (AD-iCAP) for early detection at the mild cognitive impairment/mild dementia stages. To develop the assay, patient plasma is incubated with standardized neurons, which transduce complex...

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Literature Corpus work
cb408a7e-0d6e-5523-b8f2-faa31517b96c
DOI
10.1101/2025.09.15.25335782
Open publication

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An Indicator Cell Assay-based Multivariate Blood Test for Early Detection of Alzheimer’s DiseaseDOI 10.1101/2025.09.15.25335782
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