Article

Tumor Mutational Burden Predicts Survival In Patients With Low Grade Gliomas Expressing Mutated IDH1

2020-01-23

Abstract excerpt

<h4>ABSTRACT</h4> Gliomas are the most common primary brain tumors. High Grade Gliomas have a median survival of 18 months, while Low Grade Gliomas (LGG) have a median survival of ∼7.3 years. Seventy-six percent of patients with LGG express mutated isocitrate dehydrogenase (mIDH1) enzyme (IDH1 R132H ). Survival of these patients ranges from 1-15 years, and tumor mutational burden ranges from 8 to 447 total somatic...

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Literature Corpus work: 9684d2a8-6d32-55fd-9b77-9026ee532044
DOI: 10.1101/2020.01.20.20016766

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