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Article

A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1).

Journal of neuro-oncology - 1 Sept 2013

Dahlrot Rikke H, Kristensen Bjarne W, Hjelmborg Jacob, Herrstedt Jørn, Hansen Steinbjørn

Abstract excerpt

Low-grade gliomas (LGG) have a slow growth rate, but transformations into malignant gliomas with a rapid deterioration occur in many patients. The aim of this study was to evaluate clinical prognostic factors in a population-based cohort of patients with LGG. In addition we investigated the expression and prognostic value of the isocitrate dehydrogenase 1 (IDH1) R132H mutation. Seventy-four patients diagnosed...

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Identifiers

PMID: 23817809
DOI: 10.1007/s11060-013-1186-3

Genes

IDH1

Variants

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