Article
Correlation of IDH1 mutation with clinicopathologic factors and prognosis in primary glioblastoma: a report of 118 patients from China.
PloS one - 1 Jan 2012
Yan Wei, Zhang Wei, You Gan, Bao Zhaoshi, Wang Yongzhi, Liu Yanwei, Kang Chunsheng, You Yongping, Wang Lei, Jiang Tao
Abstract excerpt
It has been reported that IDH1 (IDH1R132) mutation was a frequent genomic alteration in grade II and grade III glial tumors but rare in primary glioblastoma (pGBM). To elucidate the frequency of IDH1 mutation and its clinical significance in Chinese patients with pGBM, one hundred eighteen pGBMs were assessed by pyro-sequencing for IDH1 mutation status, and the results were correlated with clinical...
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