Article

Cell type classification and discovery across diseases, technologies and tissues reveals conserved gene signatures and enables standardized single-cell readouts

2021-02-02

Abstract excerpt

<h4>ABSTRACT</h4> Autoimmune diseases are a major cause of mortality 1,2 . Current treatments often yield severe insult to host tissue. It is hypothesized that improved “precision medicine” therapies will target pathogenic cells selectively and thus reduce or eliminate severe side effects, and potentially induce robust immune tolerance 3 . However, it remains challenging to systematically identify which cellula...

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Literature Corpus work: 0e95942e-43c0-55b4-a62d-f70359be709e
DOI: 10.1101/2021.02.01.429207

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