Article

Inhibiting the Redox Function of APE1 Suppresses Cervical Cancer Metastasis via Disengagement of ZEB1 from E-cadherin in EMT

2021-05-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Metastasis is a major challenge in cervical cancer treatment. Previous studies have shown that the dual functional protein apurinic/apyrimidinic endonuclease 1 (APE1) promotes tumor metastasis and is overexpressed in cervical cancer. However, the biological role and mechanism of APE1 in cervical cancer metastasis have rarely been studied.<bold>Methods: </bold>We...

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Literature Corpus work: 966ff434-abb3-5a86-b3ec-ba8faa41f9b1
DOI: 10.21203/rs.3.rs-152454/v1

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