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Article

APE1 promotes radiation resistance against radiation-induced pyroptosis by inhibiting the STING pathway in lung adenocarcinoma

2023-04-13

Abstract excerpt

<h4>Background: </h4> Mammalian apurinic/apyrimidinic endonuclease 1 (APE1, APEX1) is a multifunctional enzyme that maintains cell homeostasis. It is involved in the base excision repair (BER) pathway and plays a key role in radiation-induced DNA damage response. Nevertheless, the relationship between APE1-driven radiation resistance and pyroptosis in lung adenocarcinoma (LUAD) cells and the underlying molecular m...

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Literature Corpus work
5754129d-30c2-53d5-8060-283524c4fef8
DOI
10.21203/rs.3.rs-2786184/v1
Open publication

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APE1 promotes radiation resistance against radiation-induced pyroptosis by inhibiting the STING pathway in lung adenocarcinomaDOI 10.21203/rs.3.rs-2786184/v1
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