Article

Respiratory Syncytial virus NS1 protein targets the transactivator binding domain of MED25

2021-11-21

Abstract excerpt

Respiratory syncytial virus has evolved a unique strategy to evade host immune response by coding for two non-structural proteins NS1 and NS2. Recently it was shown that in infected cells, nuclear NS1 could be involved in transcription regulation of host genes linked to innate immune response, via an interaction with chromatin and the Mediator complex. Here we identified the MED25 Mediator subunit as an NS1 intera...

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Identifiers and source

Literature Corpus work: 96668e8d-448f-5d7f-830f-7aeab33e83f3
DOI: 10.1101/2021.11.19.469356

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